Ravi (Sanjay) is a desparate father who has run of all option-asking for help from his office, the insurance company, the loan sharks-to get a heart transplant he cannot afford for his son Gaurav (Pathak), who has a hole in his heart. With time running out, he takes the emergency room hostage, and laid out his terms. The police try to talk him out off it. His wife Sarita (Amisha Patel), a doctor (Jaya), a cop (Anoop), and millions of ordinary people watching the drama unfold, join his battle. Can he beat the system?

Taxi 9211 is a story about two men who have nothing in common. Raghav Shastri (Nana Patekar) or Raghu a short tempered cynic, who has changed 23 jobs in the last 15 years.... An insurance salesman to the worls but in reality, a cautic, instinctively witty cabble who needs Rs. 30,000 by the end of the day. Jai Mittal (John Abraham) the equally acidic, heir to resourceful business family has to go to court and prove his claim for Rs. 300 Crorest!! and this is his last chance. When there was no reason for them to meet, two attitudes will take a knocking. Two lives might change....