When the evil wizard Gargamel (Hank Azaria) chases the Smurfs out of their village, they're forced through a portal, out of their world and into ours, landing in the middle of New York's Central Park. Just three apples high and stuck in the Big Apple, the Smurfs must find a way to get back to their village before Gargamel tracks them down.

Flint Lockwood thinks he's a genius. But none of the things he invented are things that make sense or are useful. However, he has the support of his mother but when she dies, he's left alone with his father who thinks he should give it up. When the community that he lives in is in an economic crisis because their primary source of income, a sardine cannery, was shut down, Flint decides to try his latest invention, a machine that can turn water into food. But something goes wrong and the machine ends up in the atmosphere. Later it starts raining food. The shifty mayor tries to use this as a way to help their community, but when Flint senses something wrong with the machine, the mayor convinces him to ignore it. However, as Flint predicts, chaos ensues.

In 2009, Adrian Helmsley, an American geologist, visits astrophysicist Dr. Satnam Tsurutani in India and learns that neutrinos from a massive solar flare are causing the temperature of the Earth's core to rapidly increase. Arriving at a party in Washington D.C., Helmsley presents his info to White House Chief of Staff Carl Anheuser who takes him to meet the President. In 2010, U.S. President Thomas Wilson and other international leaders begin a secret project to ensure humanity's survival. More than 400,000 people are chosen to board enormous "arks" constructed at Cho Ming, Tibet, in the southwest Chinese Himalayas. A Buddhist monk named Nima is evacuated while his brother Tenzin joins the Ark project. Additional funding is raised by selling tickets for €1 billion per person. By 2011, valuable items are moved to the arks with the help of art expert and First Daughter Dr. Laura Wilson. In 2012, Jackson Curtis is a science fiction writer in Los Angeles who works as a limousine driver for Russian billionaire Yuri Karpov. Jackson's ex-wife Kate, and their children Noah and Lilly, live with Kate's boyfriend, plastic surgeon Gordon Silberman. Jackson takes Noah and Lilly camping in Yellowstone National Park. After an encounter with Helmsley, they meet Charlie Frost, who hosts a radio show from the park. Charlie plays a video of Charles Hapgood's theory that polar shifts and the Mesoamerican Long Count Calendar predict that the 2012 phenomenon will occur. Charlie also tells Jackson that those who discovered this and plotted to inform the public were killed in various accidents. After an earthquake hits Los Angeles, the family returns home. Jackson grows suspicious and rents a Cessna 340 to rescue his family. He collects his family and Gordon as Earth crust displacement begins with a magnitude 10.9 earthquake, and they narrowly escape Los Angeles as California collapses into the Pacific Ocean. As millions of people die in earthquakes worldwide, the group flies to Yellowstone to retrieve a map from Charlie, escaping as the Yellowstone Caldera erupts. Charlie stays behind to broadcast the eruption and is killed. Learning that the arks are in China, the group lands in Las Vegas to find a larger plane. They find Yuri, his twin sons Alec and Oleg, girlfriend Tamara and pilot Sasha. Helmsley, Anheuser, and Laura Wilson are aboard Air Force One where they are heading to the arks. President Wilson remains in Washington D.C. to address the nation one last time. With the Vice President dead and the Speaker of the House missing, Anheuser appoints himself Acting Commander in Chief even though he is not in the presidential line of succession. Back in Las Vegas, the group steals an Antonov An-500 aircraft and they depart for China as the Yellowstone ash cloud engulfs the city. President Wilson is later killed by a megatsunami that sends the aircraft carrier USS John F. Kennedy crashing into the White House. When the group arrive in China, the plane runs out of fuel and crashes into a glacier, killing Sasha, while the others make a narrow escape. They are then spotted by helicopters from the Chinese army. Yuri and his sons, possessing tickets, are taken to the arks, leaving the Curtis family and Gordon behind along with Tamara because Yuri knows she had an affair with Sasha. The remaining group are picked up by Nima and taken to the arks with her grandparents. They stow away on Ark 4, where the United States contingent is aboard, with the help of Tenzin. As a megatsunami approaches the site, an impact driver becomes lodged in the gears of the ark's hydraulic doors, preventing a boarding gate from closing, which in turn prevents the ship from starting its engines. In the ensuing chaos, Yuri, Gordon and Tamara are killed, and Ark 4 is set adrift. Jackson and Noah dislodge the impact driver and the crew regains control of the ark before it collides with Mount Everest. Jackson rejoins with his family, and he and Kate reconcile. As flood waters from the tsunamis slowly recede, the arks travel to the Cape of Good Hope in South Africa. Helmsley starts a relationship with Laura.?

While on holiday in the Irish countryside, a dysfunctional family encounters a village of deformed and homicidal residents.These residents are mostly mutant children, to whom death is all fun and games.

After falling head over hooves in love with Giselle, Elliot's road to the altar takes a slight detour when Mr. Weenie is kidnapped by a group of pampered pets determined to return him to his owners.

A grizzly bear named Boog, domesticated by a park ranger, Beth, helps deer friend Elliot escape from the mullet-sporting hunter, Shaw. When the Elliot decides to return the favor to help Boog escape from Beth he finds that Boog is very happy with his domesticated home. After a misunderstanding, Beth is convinced that Boog is reverting to his wild nature and releases him in the woods just as hunting season begins. Boog has no idea how to survive outside of his garage home with his beloved Beth. Elliott and Boog develop a strong bond not only between themselves but also with the wild animals and attempt to drive the hunters out of the forest.

In 1944, a woman had a boyfriend and was going to get engaged. But her father thought he was poor and tried to use a gun. 63 Years later, moving to a spooky, old house in the country, Roxy Hunter, an irrepressible nine-year old, stumbles into a weird world of unsolved mysteries and the unknown. With the help of her best friend Max, a twelve-year-old genius she calls her fiancé, she embarks on a mission to solve a crime, save their house, and re-unite a lost love from beyond the grave.

Former superhero Jack Shepard, (also known as Captain Zoom), is called back to work to transform an unlikely group of ragtag kids into a new generation of superheroes at a privacy Academy and save the world from certain destruction. The project holds an audition of would-be members, most of whom possess useless or disgusting powers. In the end, Dylan, a 17-year-old boy who can turn invisible Summer, a 16-year-old girl with telekinetic powers Tucker, a 12-year-old boy with the power to enlarge any part of his body Cindy, a 6-year-old girl with super strength.

Two scientists, Dr. Elena Kinder (Diane Keaton) and Dr. Heep (Christopher Lloyd), use genius-baby studies to fund BabyCo's theme park "Joyworld". According Dr. Kinder's Research, babies are supposed to possess vast, universal knowledge and speak a secret yet impossible-to-translate baby prelanguage called "Babytalk". At age two, however, the knowledge and language are lost as the babies "cross over" by learning how to talk. Most of the babies that were raised in Dr. Kinder's vast, underground research facility were adopted from the Pasadena orphanage, transformed into geniuses through use of the Kinder Method, and then used in experiments to decipher the language used by the baby-geniuses. One mischievous toddler, Sylvester (AKA Sly), makes repeated attempts to escape Dr. Kinder's research facility and one night, Sylvester goes into a dirty diaper truck and he actually succeeds. The next morning, one things Sylvester does not expect is to run into his twin, Whit, in a mall playground. Although Sylvester and Whit share a telepathic bond, they have no idea of each other's existence. While the guards from Dr. Kinder's research facility capture Whit, mistake him for Sylvester, and take him back to Dr. Kinder's research facility, Sylvester is taken home by Whit's adopted mother, Robin (Kim Cattrall), who is Dr. Kinder's niece. After Dr. Kinder is horrified that Whit and Sylvester switched at the mall, she decides to do a cross evaluation on Sylvester and Whit. However, when she comes to Dan Bobbin's place, she realizes that Dan Bobbin can understand babies. After the attempts to retrieve Sylvester fail, Dr. Kinder decides to move the research facility to Lichtenstein, so that they can transform Whit into becoming a genius thanks to him getting bred by the Kinder Method (thus erasing his memories about his foster parents, foster brothers and foster sisters) and use him as an experiment to crack the code to "Babytalk". The babies at Bobbin's place hypnotize Lenny (Dom DeLuise), the bus driver to drive to Dr. Kinder's research facility. Once at the research facility, Sylvester goes to the control room to set the robots from the theme park on the lab scientists. When the Bobbins return home, their natural daughter Carrie tells her father that the children are in Dr. Kinder's research facility. At the end of the fight Dr. Kinder captures Whit and takes him to the helicopter pad on the roof. Robin and Dan chase them to the roof, where Dr. Kinder reveals that she and Robin are not related, and that Robin was adopted at age two. After Dr. Kinder got arrested by the police, Sylvester and Whit come together on the roof to cross over. Dan and Robin adopt Sylvester. Dan is still curious of the secrets of life, but as the twins have crossed over they no longer know those secrets. Carrie, their sister, doesn't reveal anything (just gives her dad a sly smile) because adults aren't meant to know their secrets.