Taxi 9211 is a story about two men who have nothing in common. Raghav Shastri (Nana Patekar) or Raghu a short tempered cynic, who has changed 23 jobs in the last 15 years.... An insurance salesman to the worls but in reality, a cautic, instinctively witty cabble who needs Rs. 30,000 by the end of the day. Jai Mittal (John Abraham) the equally acidic, heir to resourceful business family has to go to court and prove his claim for Rs. 300 Crorest!! and this is his last chance. When there was no reason for them to meet, two attitudes will take a knocking. Two lives might change....

Rohit Mehra (Hrithik Roshan), who shows the world that friendship is truly universal. Sanjay Mehra is a scientist obsessed with establishing contact with extraterrestrial life. He invents many innovative gadgets, instruments and finally succeeds in devising a computer that can transmit messages to space. His foresight becomes reality when as a response to his signals, a spaceship is sighted in the sky. But before Sanjay can even enjoy his success, he and his wife Sonia meet with a horrific accident where Somia survives but Sanjay loses his life.