Hum Tum is a new and refreshing look at the eternal battle of the sexes as it follows the lives of Karan and Rhea. Karan is a cartoonist and his cartoon characters "Hum" and "Tum" are very popular. Hum Tum reflect Karan's perspective on men and women and their strange relationship. Karan is the quintessential bad boy-he is a complete flirt, and is constantly changing girlfriends. Rhea is sensitive, well bred and with high ethical and moral standards. The two come from very different backgrounds, and have evolved into very different people. Whereas Karan's father-s flamboyant famous fashion photographer, has influenced his son to be nonchalant and cool, Rhea gets her self- assuredness and moral code from her mother- a typical Punjabi with an effervescent spirit.....

Auto engineer Aditya (Akshay Kumar) and talented dress designer, Sonia (Bipasha Basu) are engaged to be married. Adi leave for Canada for training while Sonia takes off to France for a fashion show. In Canada, Adi meets the gorgeous Jia (Katrina) who's shopping for her marriage to an affluent entrepreneur, Karan. Jia is a girl of simple taste who craves for companionship, which her tycoon father and fiancee cannot give. Adi enters her life like a saviour... and friendship turns to love. A misunderstanding drives them apart... she to resumes marriage plans to Karan, and he to Sonia. Does true love find its way? Or do lovers make peace with their destiny?Fate intervenes when they meet for one last time at Jia's wedding.

CG (Ajay Devgan) is the man who started with nothing and now believes that only money can fuel his ambition. While Guruji (Jawed Sheikh), to the manor born, believes that wealth means nothing if not used for the good of society. Caught in the tussle between the two is the unworldly, Jaidev Vardahn (Shahid Kapoor) who while respecting his father's philosophy, falls hook, line and sinker for CG's gift-edged dreams. WHile Guruji hopes that Jai will return to his roots. CG uses the glamorous Natasha (Bipasha Basu) to bewitch Jai and an unscrupulous politician, to exploit the tribals into selling their lands. Madhavi (Amrita Rao) watches the man she loves being trapped in a world of wine, women and wealth.

Ravi (Sanjay) is a desparate father who has run of all option-asking for help from his office, the insurance company, the loan sharks-to get a heart transplant he cannot afford for his son Gaurav (Pathak), who has a hole in his heart. With time running out, he takes the emergency room hostage, and laid out his terms. The police try to talk him out off it. His wife Sarita (Amisha Patel), a doctor (Jaya), a cop (Anoop), and millions of ordinary people watching the drama unfold, join his battle. Can he beat the system?

In 19th century New Mexico, a father comes home hoping to reconcile with his daughter, Maggie. Maggie's daughter is kidnapped, forcing father and daughter to work together to get her back.